Resources for NIH NIGMS R01GM068946

Grant description

Mathematic descriptions - multifactorial gene expression funded by NIH / NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

Beehive and bee related resources

Objectives

  1. Characterization of gene expression patterns for social behavior as a function of age and genotype
    Whitfield CW, Ben-Shahar Y, Brillet C, Leoncini I, Crauser D, Leconte Y, Rodriguez-Zas S, Robinson GE. "Genomic dissection of behavioral maturation in the honey bee". Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16068-75.
  2. Development and implementation of longitudinal linear and nonlinear models to describe changes in gene expression across ages.
    Rodriguez-Zas SL, Southey BR, Whitfield CW, Robinson GE. Semiparametric approach to characterize unique gene expression trajectories across time. BMC Genomics. 2006 Sep 13;7:233.
  3. Development and implementation of hierarchical linear models to investigate the gene expression profiles across bee genotypes.
    Abstract sumbmitted to the 2007 American Statisical Association meeting.
  4. Assessment of model fit and confidence intervals using novel graphical approaches
  5. Development of public, user-friendly, free software that integrates the developed analysis and visualization tools with bioinformatic databases and tools.
  6. Communication of general mathematical and biology concepts and project findings through workshops and development of educational materials customized to different audiences